DOUXO® S3 PYO Shampoo
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Antiseptic Shampoo – cleans while hydrating the skin
- Cleanses and fights bacterial and yeast skin infections, while strengthening and hydrating your pet’s skin.**
- Leaves the Coat Soft, Shiny, and Lightly Scented
- DOUXO® S3 PYO products contain chlorhexidine digluconate 3%, which has antiseptic properties.
- DOUXO® S3 PYO is free of soap, sulphates, parabens, nanoparticles, colorant, phthalates, and silicones.
Safe for you and your pet
20+ years of expertise
90% of pet owners are satisfied with the DOUXO®S3 routine1,2
#1 topical brand recommended by veterinarians*
Benefits

For bacterial or yeast skin infections.
Clinically proven to fight bacterial and fungal skin infections.⁴,⁵,⁶
Helps detangle the fur and leaves the coat soft and shiny.
Composition

Contains 3% Chlorhexidine*** & 0.5% Ophytrium®
DOUXO® S3 range is the only pet skin care line that contains Ophytrium®, an exclusive purified natural ingredient selected for its safety and threefold action on the skin barrier.⁷,⁸
Our formula is free from soaps, sulphates, parabens, colorants, nanoparticles, phthalates, silicones.
How to use

Directions
To know more about how to apply the products, watch our dedicated video:
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©2024 Ceva Animal Health, LLC DOUXO®, the DOUXO® S3 logo, OPHYTRIUM® and the OPHYTRIUM® logo are registered trademarks of Ceva Santé Animale S.A.
*Based on a survey of 400 veterinarians.
**Ollivier E., Gatellet M., Jamet J.F., Pradies F., Ilgart E., Piault C., Fiora P., De-Jaeger X. (2022). Performance of a protocol combining applications of Ophytrium- and chlorhexidine-containing shampoo and mousse in dogs with Malassezia overgrowth. BSAVA congress, Manchester, UK, March 24-26th.
***Chlorhexidine can cause rare but serious allergic reactions in humans. If an allergic reaction occurs, discontinue use and seek immediate medical treatment. Do not use DOUXO® S3 PYO Mousse on cats. Do not use DOUXO® S3 PYO Pads between the toes of cats.
1 Ollivier E., Ordeix L., Kesteman R., Blondel T., Zemirline C., Gatellet M., De Jaeger X (2021). Effect of a protocol combining applications of Ophytrium-based shampoo and mousse in dogs with sensitive, itchy and irritated skin - A European and US field trial. 15th UNISVET congress, Italy, February 25-28th.
2 Gatellet M., Ahman S., Bruet V., Cadot P-M., Mueller R., Noli C., Nuttall T., Ollivier E., Blondel T., Savelli N. (2020). Performance of combined shampoo and mousse applications containing Ophytrium and Seboliance in dogs with scaling disorders: a European field trial. Vet Dermatol. 31 (Supl1):33
3 Gatellet M., Bruet V., Cadot P-M., Laffort C., Noli C., Ordeix L., Kesteman R., Ollivier E., De-Jaeger X. (2020). Performance of two protocols combining Chlorhexidine digluconate3%- and Ophytrium-based shampoo and mousse applications in the management of bacterial overgrowth in dogs. 14th UNISVET national congress, Milan, Italy, February 14-16th.
4 Gatellet M., Kesteman R., Baulez B., Pradiès F., Cadot P.M., Dropsy H., Fiora P., Mathet J.L., Ollivier E., Billy C., De Jaeger X. (2021). Performance of daily pads containing Ophytrium and chlorhexidine digluconate 3% in dogs with local cutaneous bacterial and/or Malassezia overgrowth. Front Vet Sci 8:579074.
5 Ollivier, E., Savelli, N., Rossi, M., Torres, S., Lewis, T., Bourgeois, A., Griffin, J., Ramos, S., Gatellet, M. (2022). Performance of a protocol combining applications of OphytriumTM- and chlorhexidine-containing shampoo and mousse in dogs with bacterial and/or Malassezia overgrowth: a U.S. multicentric prospective field trial. NAVDF, New-Orleans, USA, April 27-30th.
6 Ollivier E., Zemirline C., Amalric N., Rahoul V., Reymond N., Cadiergues M-C. (2019). Efficacy of the ingredient A97614A1 in a model of reconstructed human epidermis stressed by cytokines. Proceedings of the 62nd BS VA Congress. Birmingham, UK, April 4-7th.
7 Ollivier E., Zemirline C., Marchand L., Closs B. (2019). Effect of the ingredient A97614A1 on the adhesion and biofilm formation of Staphylococcus pseudintermedius in a model of reconstructed canine epidermis. Proceedings of the 62nd BSAVA Congress. Birmingham, UK, April 4-7th.